Aging is due to oxidative stress that takes place in our body. Oxidative Stress is not a disease in and of itself, it is a precursor to all degenerative disease. The body regenerates itself entirely every 7 years, yet for some reason as we age the body breaks down. It seems when we reach 60, 70 or 80 the process of decline accelerates. This oxidative stress is due to the present of free radicals. The answer to free radicals are antioxidants! They are compounds that can donate an electron to a free radical so that the free radical doesn’t have to take the electron from the skin’s atoms. We can illustrate this oxidative stress by the oxidation that take place is an apple.
Aging and Skin damage by Free Radicals.
Free radicals can be created from pollution such as smog, dust and cigarette smoke, as well as our good friend the sun. Skin damage done by free radicals may appear in several forms. They range from changes in skin color (brown spots and broken blood vessels) to weakened skin that looks loose and saggy as a result of damaged elastic fibers. Free radicals can also break down the skin’s collagen and create wrinkles.
Benefits of H2 for Anti-Aging and Skin Care.
Combatting premature aging isn’t just about reversing the effects of time on your looks – it’s also about how you feel on a day-to-day basis.
Oxidative stress plays a central role in skin aging at the cellular level. Free radicals break down collagen, affect cellular renewal cycles, damage the skin’s cellular DNA, and promote the release of pro-inflammatory substances that contribute to various skin diseases and age spots. Molecular hydrogen fights the most damaging free radicals within the cells, protecting and rejuvenating your skin, while improving its tone, texture, and elasticity, and promoting skin rejuvenation.
By Perdita Nouril,
Since the Eighties, the anti-ageing ingredient retinol (vitamin A) has been touted as the biggest boon for beauty. Yet famed dermatologist Dr Perricone believes harnessing hydrogen is a far more efficacious way to wage war on wrinkles.
For those who have a foggy memory of secondary school chemistry, hydrogen is the smallest and most basic molecule, representing more than 90 percent of the matter in the universe. It’s widely tipped as the most promising source of “clean” fuel on Earth, and has now been bestowed with a skin-enhancing halo, thanks to its unrivaled anti-inflammatory properties.
Hydrogen’s healing history
Drinking and even bathing in hydrogen-infused water has long been an obsession of the Japanese, who commend its youth-giving and health healing properties. Known as Shin’nooru, it’s so popular that tech companies, including Panasonic, sell machines that allow you to enrich your water with hydrogen at home. A recent Japanese study in the Journal of Photochemistry and Photobiology confirmed what locals had been preaching for years and found that bathing in hydrogen water every day for three months can reduce neck wrinkles. Similarly, a control group of UV-damaged human fibroblasts (the cell responsible for producing collagen in your skin) were shown to increase collagen production twice over after being soaked in hydrogen water for 72 hours.
How hydrogen turns back the clock
“Hydrogen works by positively affecting gene regulation, gene expression, and silencing negative genes,” explains Dr Perricone. “It’s a very clever molecule because its powerful anti-inflammatory superpowers target and neutralise inflammation-causing free radicals, which are caused by stress, lack of sleep, pollution and UVA and UVB rays.”
Because hydrogen is the smallest molecule, it easily passes through the cell membrane. So its able to wiggle its way into the mitochondria, (the energy centers of a skin cell) and it’s also able to penetrate the nucleus of a cell where the DNA is stored. Once there, its able to neutralise and reduce free radicals linked to ageing.
Hydrogen’s real pièce de résistance is that its able to up-regulate ‘messenger molecules’, which essentially tell cells to produce hundreds of antioxidant enzymes to counteract free radicals. In layman’s terms, hydrogen encourages your cells to become an antioxidant factory. And unlike vitamin C or other antioxidants, you can’t use them all up because the hydrogen is boosting your skins ability to create new ones.
“Hydrogen-rich electrolyzed warm water represses wrinkle formation against UVA ray together with type-I collagen production and oxidative-stress diminishment in fibroblasts and cell-injury prevention in keratinocytes.” Kato S1, Saitoh Y, Iwai K, Miwa N.
Hydrogen-rich electrolyzed warm water (HW) was prepared at 41°C and exhibited dissolved hydrogen (DH) of 1.13 ppm and an oxidation-reduction potential (ORP) of -741 mV in contrast to below 0.01 ppm and+184 mV for regular warm water (RW). Fibroblasts OUMS-36 and keratinocytes HaCaT were used to examine effects of HW against UVA-ray irradiation. Type-I collagen was synthesized 1.85- to 2.03-fold more abundantly by HW application for 3-5 days than RW in OUMS-36 fibroblasts, and localized preferentially around the nuclei as shown by immunostain. HW application significantly prevented cell death and DNA damages such as nuclear condensation and fragmentation in UVA-irradiated HaCaT keratinocytes as estimated by WST-1 and Hoechst 33342 assays. HW significantly suppressed UVA-induced generation of intracellular superoxide anion radicals in both the cell lines according to NBT assay. Wrinkle repression was clinically assessed using a HW-bathing. Six Japanese subjects were enrolled in a trial of HW-bathing (DH, 0.2-0.4 ppm) every day for 3 months. HW-bathing significantly improved wrinkle in four subjects on the back of neck on 90th day as compared to 0 day. Thus, HW may serve as daily skin care to repress UVA-induced skin damages by ROS-scavenging and promotion of type-I collagen synthesis in dermis.
Dr. Elen speaks on the positive effect of molecular hydrogen on Aging.
Hydrogen-rich electrolyzed warm water represses wrinkle formation against UVA ray together with type-I collagen production and oxidative-stress diminishment in fibroblasts and cell-injury prevention in keratinocytes.
Kato S, Kikuchi R, Aoshima H, Saitoh Y, Miwa N.
Saitoh Y, Miyanishi A, Mizuno H, Kato S, Aoshima H, Kokubo K, Miwa N.
Kato S, Aoshima H, Saitoh Y, Miwa N.